Abstract Search

ea0040p4 | (1) | ESEBEC2016

Expression of osteopontin isoforms is related with thyroid cancer growth and invasion

Ferreira Luciana Bueno , Tavares Catarina , Pestana Ana , Leite Catarina , Eloy Catarina , Rios Elisabete , Celestino Ricardo , Batista Rui , Sobrinho-Simoes Manuel , Gimba Etel , Soares Paula

Osteopontin (OPN) is a matricellular protein highly expressed in cancer cells, which is able to modulate tumorigenesis and metastasis in several malignancies, including follicular cell-derived thyroid cancers (TC). OPN is one of the gene products aberrantly expressed in TC, but the contribution of each OPN isoform (OPNi), named as OPNa, OPNb and OPNc, is currently unknown. This study aims to analyze the expression profile of OPNi in TC tissue samples, correlate its expression ...

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ea0049ep1449 | Thyroid (non-cancer) | ECE2017

The usefulness of the study of sodium iodide symporter expression in thyroid primary tumors

Tavares Catarina , Coelho Maria Joao , Eloy Catarina , Melo Miguel , da Rocha Adriana Gaspar , Pestana Ana , Batista Rui , Ferreira Luciana Bueno , Rios Elisabete , Cavadas Bruno , Pereira Luisa , Selmi-Ruby Samia , Simoes Manuel Sobrinho , Soares Paula

Thyroid cancer therapy is based on surgery followed by radioiodine treatment of tumor remnants and metastases. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS), normally present in thyroid follicular cells membrane. We studied the expression of NIS in a series of 229 thyroid primary tumors using real time PCR and immunohistochemistry, and searched for possible associations between NIS expression and clinicopathological feature...

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Endocrine Abstracts

Expression of osteopontin isoforms is related with thyroid cancer growth and invasion

The usefulness of the study of sodium iodide symporter expression in thyroid primary tumors

BiosciAbstracts